This product is for R&D purposes only and is not approved for human or veterinary use.
SS-31
SS-31 (Elamipretide research compound) is a laboratory-supplied compound intended for use in qualified research and institutional settings. This product is provided strictly for research purposes only and is commonly used in experimental studies investigating mitochondrial membrane interactions, phospholipid binding dynamics, and subcellular targeting mechanisms under controlled conditions.
Research Context
SS-31 is a synthetic aromatic-cationic tetrapeptide belonging to the Szeto-Schiller peptide series, and is widely studied in mitochondrial biology and cellular bioenergetics research environments. It is frequently examined for its selective association with cardiolipin, a phospholipid localized to the inner mitochondrial membrane, and for its capacity to accumulate in subcellular compartments independently of membrane potential in experimental models. In research settings, SS-31 is commonly explored for its interaction with electron transport chain complexes, cristae membrane architecture, and cytochrome c binding dynamics. Investigators also study its structural motif of alternating aromatic and basic residues, its cell-permeability characteristics, and comparative behavior alongside other mitochondria-targeted compounds, making it a frequent reference compound in experimental models examining mitochondrial membrane organization.
Research Overview
SS-31 is utilized in controlled laboratory workflows to support in vitro and in vivo investigations, including assays evaluating phospholipid binding affinity, mitochondrial localization, and bioenergetic parameter measurement. Researchers may employ this compound in biochemical assays, cell culture experiments, isolated mitochondria preparations, and experimental model systems to evaluate peptide uptake, membrane association, and organelle-level response under varying conditions.
Key Research Focus Areas
Cardiolipin & Membrane Binding: Investigating phospholipid interaction, binding selectivity, and inner mitochondrial membrane association in controlled assay conditions.
Mitochondrial Bioenergetics: Studying electron transport chain activity, oxidative phosphorylation efficiency, and respiratory capacity in experimental models.
Redox & Oxidative Stress Models: Examining reactive oxygen species dynamics, cytochrome c interactions, and redox state measurement in laboratory conditions.
Peptide Structure-Activity Studies: Evaluating aromatic-cationic residue patterning, sequence-dependent uptake, and structural stability relative to related Szeto-Schiller analogs.
Store refrigerated at 2–8°C. Protect from light and moisture.
Intended Use
For laboratory research use only. Not for human or veterinary use.
Analytical verification documentation may be available upon request for qualified research institutions.
This research compound is provided in a controlled formulation intended to support stability, consistency, and reproducibility in laboratory workflows. Researchers should follow institutional safety standards, ethical protocols, and approved handling procedures when conducting experiments involving peptide compounds.
For research use only. Not for human or animal consumption.
This product has multiple variants. The options may be chosen on the product page
BATS Testing in progress
CERTIFICATE OF ANALYSIS COMING SOON
This product is currently undergoing third-party batch testing at our U.S.-based laboratory. The Certificate of Analysis will be published here once verification is complete.
COAs are typically available within a few business days of a new batch release.
